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Conformation of the AcrB Multidrug Efflux Pump in Mutants of the Putative Proton Relay Pathway
We previously reported the X-ray structures of wild-type Escherichia coli AcrB, a proton motive force-dependent multidrug efflux pump, and its N109A mutant. These structures presumably reflect the resting state of AcrB, which can bind drugs. After ligand binding, a proton may bind to an acidic resid...
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| Main Authors: | , , , , , , |
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| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
American Society for Microbiology
2006
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1636240/ https://ncbi.nlm.nih.gov/pubmed/17015668 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00684-06 |
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