Rapid stimulation of tyrosine phosphorylation signals downstream of G-protein-coupled receptors for thromboxane A(2) in human platelets

Signals ensuing from trimeric G-protein-coupled receptors synergize to induce platelet activation. At low doses, the thromboxane A(2) analogue U46619 does not activate integrin αIIbβ3 or trigger platelet aggregation, but it induces shape changes. In the present study, we addressed whether low doses...

Full description

Saved in:
Bibliographic Details
Main Authors: Minuz, Pietro, Fumagalli, Laura, Gaino, Stefania, Tommasoli, Rosa M., Degan, Maurizio, Cavallini, Chiara, Lecchi, Anna, Cattaneo, Marco, Lechi Santonastaso, Clara, Berton, Giorgio
Format: Artigo
Language:Inglês
Published: Portland Press Ltd. 2006
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1635449/
https://ncbi.nlm.nih.gov/pubmed/16859489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20061015
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items