Physical and functional interactions between MutY glycosylase homologue (MYH) and checkpoint proteins Rad9–Rad1–Hus1

The MYH (MutY glycosylase homologue) increases replication fidelity by removing adenines or 2-hydroxyadenine misincorporated opposite GO (7,8-dihydro-8-oxo-guanine). The 9-1-1 complex (Rad9, Rad1 and Hus1 heterotrimer complex) has been suggested as a DNA damage sensor. Here, we report that hMYH (hum...

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Bibliographic Details
Main Authors: Shi, Guoli, Chang, Dau-Yin, Cheng, Chih-Chien, Guan, Xin, Venclovas, Česlovas, Lu, A-Lien
Format: Artigo
Language:Inglês
Published: Portland Press Ltd. 2006
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1635441/
https://ncbi.nlm.nih.gov/pubmed/16879101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20060774
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