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Differential cooperation of oncogenes with p53 and Bax to induce apoptosis in rhabdomyosarcoma
BACKGROUND: Deregulated expression of oncogenes such as MYC and PAX3-FKHR often occurs in rhabdomyosarcomas. MYC can enhance cell proliferation and apoptosis under specific conditions, whereas PAX3-FKHR has only been described as anti-apoptotic. RESULTS: In order to evaluate how MYC and PAX3-FKHR on...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2006
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1635425/ https://ncbi.nlm.nih.gov/pubmed/17081294 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-5-53 |
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