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Initiation of Attachment and Generation of Mature Focal Adhesions by Integrin-containing Filopodia in Cell Spreading

Integrin receptors, and associated cytoplasmic proteins mediate adhesion, cell signaling and connections to the cytoskeleton. Using fluorescent protein chimeras, we analyzed initial integrin adhesion in spreading fibroblasts with Total Internal Reflection Fluorescence (TIRF) microscopy. Surprisingly...

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Bibliographic Details
Main Authors: Partridge, Michael A., Marcantonio, Eugene E.
Format: Artigo
Language:Inglês
Published: The American Society for Cell Biology 2006
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1635363/
https://ncbi.nlm.nih.gov/pubmed/16855018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E06-06-0496
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