Structure-activity relationships of quinolone agents against mycobacteria: effect of structural modifications at the 8 position.

A series of quinolones with substitutions at the 8 position has been prepared as part of a study to examine the relationship between structural modifications at this position and activity against mycobacteria. The compounds were prepared by procedures described in the literature and were evaluated f...

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Publicado en:	Antimicrob Agents Chemother
Autores principales:	Renau, T E, Gage, J W, Dever, J A, Roland, G E, Joannides, E T, Shapiro, M A, Sanchez, J P, Gracheck, S J, Domagala, J M, Jacobs, M R, Reynolds, R C
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Microbiology (ASM) 1996
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163535/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8891145/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.40.10.2363
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