Structure-activity relationships of quinolone agents against mycobacteria: effect of structural modifications at the 8 position.

A series of quinolones with substitutions at the 8 position has been prepared as part of a study to examine the relationship between structural modifications at this position and activity against mycobacteria. The compounds were prepared by procedures described in the literature and were evaluated f...

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Main Authors: Renau, T E, Gage, J W, Dever, J A, Roland, G E, Joannides, E T, Shapiro, M A, Sanchez, J P, Gracheck, S J, Domagala, J M, Jacobs, M R, Reynolds, R C
Format: Artigo
Sprog:Inglês
Udgivet: 1996
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC163535/
https://ncbi.nlm.nih.gov/pubmed/8891145
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