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Interaction between Miltefosine and Amphotericin B: Consequences for Their Activities towards Intestinal Epithelial Cells and Leishmania donovani Promastigotes In Vitro

The aim of this study was to evaluate the potential of a combination of two antileishmanial drugs, miltefosine (HePC) and amphotericin B (AMB), when administered by the oral route. Caco-2 cell monolayers were used as a validated in vitro model of the intestinal barrier and Leishmania donovani promas...

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Detalhes bibliográficos
Main Authors: Ménez, Cécile , Buyse, Marion, Besnard, Madeleine, Farinotti, Robert, Loiseau, Philippe M., Barratt, Gillian
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1635231/
https://ncbi.nlm.nih.gov/pubmed/16966395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00837-06
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