Direct evidence for antipseudomonal activity of macrolides: exposure-dependent bactericidal activity and inhibition of protein synthesis by erythromycin, clarithromycin, and azithromycin.

Several previous investigators have reported that long-term administration of certain macrolides is efficacious in patients with persistent pulmonary Pseudomonas aeruginosa infections, even though the clinically achievable concentrations of these medications are far below their MICs. In the present...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Tateda, K, Ishii, Y, Matsumoto, T, Furuya, N, Nagashima, M, Matsunaga, T, Ohno, A, Miyazaki, S, Yamaguchi, K
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163517/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8891128/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.40.10.2271
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