Direct evidence for antipseudomonal activity of macrolides: exposure-dependent bactericidal activity and inhibition of protein synthesis by erythromycin, clarithromycin, and azithromycin.

Several previous investigators have reported that long-term administration of certain macrolides is efficacious in patients with persistent pulmonary Pseudomonas aeruginosa infections, even though the clinically achievable concentrations of these medications are far below their MICs. In the present...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Tateda, K, Ishii, Y, Matsumoto, T, Furuya, N, Nagashima, M, Matsunaga, T, Ohno, A, Miyazaki, S, Yamaguchi, K
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1996
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163517/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8891128/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.40.10.2271
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