Direct evidence for antipseudomonal activity of macrolides: exposure-dependent bactericidal activity and inhibition of protein synthesis by erythromycin, clarithromycin, and azithromycin.

Several previous investigators have reported that long-term administration of certain macrolides is efficacious in patients with persistent pulmonary Pseudomonas aeruginosa infections, even though the clinically achievable concentrations of these medications are far below their MICs. In the present...

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Bibliografiske detaljer

Udgivet i:	Antimicrob Agents Chemother
Principais autores:	Tateda, K, Ishii, Y, Matsumoto, T, Furuya, N, Nagashima, M, Matsunaga, T, Ohno, A, Miyazaki, S, Yamaguchi, K
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 1996
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163517/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8891128/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.40.10.2271
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