Gene transfer in humans using a conditionally replicating lentiviral vector

We report findings from a clinical evaluation of lentiviral vectors in a phase I open-label nonrandomized clinical trial for HIV. This trial evaluated the safety of a conditionally replicating HIV-1-derived vector expressing an antisense gene against the HIV envelope. Five subjects with chronic HIV...

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Detalhes bibliográficos
Main Authors: Levine, Bruce L., Humeau, Laurent M., Boyer, Jean, MacGregor, Rob-Roy, Rebello, Tessio, Lu, Xiaobin, Binder, Gwendolyn K., Slepushkin, Vladimir, Lemiale, Franck, Mascola, John R., Bushman, Frederic D., Dropulic, Boro, June, Carl H.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1635018/
https://ncbi.nlm.nih.gov/pubmed/17090675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0608138103
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