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Group of peptides that act synergistically with hydrophobic antibiotics against gram-negative enteric bacteria.

A synthetic peptide, KFFKFFKFFK [corrected], consisting of cationic lysine residues and hydrophobic phenylalanine residues was found to sensitize gram-negative bacteria to hydrophobic and amphipathic antibiotics. At a concentration of 3 micrograms/ml, it decreased the MIC of rifampin for smooth, enc...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Vaara, M, Porro, M
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163420/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8843284/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.40.8.1801
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