Group of peptides that act synergistically with hydrophobic antibiotics against gram-negative enteric bacteria.
A synthetic peptide, KFFKFFKFFK [corrected], consisting of cationic lysine residues and hydrophobic phenylalanine residues was found to sensitize gram-negative bacteria to hydrophobic and amphipathic antibiotics. At a concentration of 3 micrograms/ml, it decreased the MIC of rifampin for smooth, enc...
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| Udgivet i: | Antimicrob Agents Chemother |
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| Principais autores: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology (ASM)
1996
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163420/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8843284/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.40.8.1801 |
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