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Group of peptides that act synergistically with hydrophobic antibiotics against gram-negative enteric bacteria.

A synthetic peptide, KFFKFFKFFK [corrected], consisting of cationic lysine residues and hydrophobic phenylalanine residues was found to sensitize gram-negative bacteria to hydrophobic and amphipathic antibiotics. At a concentration of 3 micrograms/ml, it decreased the MIC of rifampin for smooth, enc...

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Autors principals: Vaara, M, Porro, M
Format: Artigo
Idioma:Inglês
Publicat: 1996
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC163420/
https://ncbi.nlm.nih.gov/pubmed/8843284
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