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Multiple pathways of selected gene amplification during adaptive mutation

In a phenomenon referred to as “adaptive mutation,” a population of bacterial cells with a mutation in the lac operon (lac(−)) accumulates Lac(+) revertants during prolonged exposure to selective growth conditions (lactose). Evidence was provided that selective conditions do not increase the mutatio...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kugelberg, Elisabeth, Kofoid, Eric, Reams, Andrew B., Andersson, Dan I., Roth, John R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2006
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1633709/
https://ncbi.nlm.nih.gov/pubmed/17082307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0608309103
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