Reporter gene technology to assess activity of antimycobacterial agents in macrophages.
Reporter strains of Mycobacterium tuberculosis and Mycobacterium bovis BCG endogenously expressing firefly luciferase were used in bioluminescence assays to evaluate the activities of isoniazid and rifampin against mycobacteria sequestered in human macrophages. This methodology allowed the efficacy...
保存先:
| 出版年: | Antimicrob Agents Chemother |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Microbiology (ASM)
1996
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163365/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8726035/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.40.6.1542 |
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