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Reporter gene technology to assess activity of antimycobacterial agents in macrophages.

Reporter strains of Mycobacterium tuberculosis and Mycobacterium bovis BCG endogenously expressing firefly luciferase were used in bioluminescence assays to evaluate the activities of isoniazid and rifampin against mycobacteria sequestered in human macrophages. This methodology allowed the efficacy...

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Sábháilte in:
Sonraí bibleagrafaíochta
Foilsithe in:Antimicrob Agents Chemother
Príomhchruthaitheoirí: Arain, T M, Resconi, A E, Singh, D C, Stover, C K
Formáid: Artigo
Teanga:Inglês
Foilsithe / Cruthaithe: American Society for Microbiology (ASM) 1996
Ábhair:
Rochtain ar líne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163365/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8726035/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.40.6.1542
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