Bisbenzylisoquinolines as modulators of chloroquine resistance in Plasmodium falciparum and multidrug resistance in tumor cells.

Ten naturally occurring bisbenzylisoquinolines (BBIQ) and two dihydro derivatives belonging to five BBIQ subgroups were evaluated in vitro for their ability to inhibit Plasmodium falciparum growth and, in drug combination, to reverse the resistance to chloroquine of strain FcB1. The same alkaloids w...

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Main Authors: Frappier, F, Jossang, A, Soudon, J, Calvo, F, Rasoanaivo, P, Ratsimamanga-Urverg, S, Saez, J, Schrevel, J, Grellier, P
Formáid: Artigo
Teanga:Inglês
Foilsithe: 1996
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC163352/
https://ncbi.nlm.nih.gov/pubmed/8726022
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