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On the Mechanism of Chloroquine Resistance in Plasmodium falciparum
Resistance to chloroquine of malaria strains is known to be associated with a parasite protein named PfCRT, the mutated form of which is able to reduce chloroquine accumulation in the digestive vacuole of the pathogen. Whether the protein mediates extrusion of the drug acting as a channel or as a ca...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2988812/ https://ncbi.nlm.nih.gov/pubmed/21124966 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0014064 |
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