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On the Mechanism of Chloroquine Resistance in Plasmodium falciparum

Resistance to chloroquine of malaria strains is known to be associated with a parasite protein named PfCRT, the mutated form of which is able to reduce chloroquine accumulation in the digestive vacuole of the pathogen. Whether the protein mediates extrusion of the drug acting as a channel or as a ca...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Chinappi, Mauro, Via, Allegra, Marcatili, Paolo, Tramontano, Anna
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2010
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2988812/
https://ncbi.nlm.nih.gov/pubmed/21124966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0014064
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