Bisbenzylisoquinolines as modulators of chloroquine resistance in Plasmodium falciparum and multidrug resistance in tumor cells.

Ten naturally occurring bisbenzylisoquinolines (BBIQ) and two dihydro derivatives belonging to five BBIQ subgroups were evaluated in vitro for their ability to inhibit Plasmodium falciparum growth and, in drug combination, to reverse the resistance to chloroquine of strain FcB1. The same alkaloids w...

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Detalhes bibliográficos
Main Authors: Frappier, F, Jossang, A, Soudon, J, Calvo, F, Rasoanaivo, P, Ratsimamanga-Urverg, S, Saez, J, Schrevel, J, Grellier, P
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC163352/
https://ncbi.nlm.nih.gov/pubmed/8726022
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