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Identification of novel thiocarboxanilide derivatives that suppress a variety of drug-resistant mutant human immunodeficiency virus type 1 strains at a potency similar to that for wild-type virus.

A large variety of carboxanilide and thiocarboxanilide derivatives in which the original oxathiin or aliphatic moieties present in the prototype compounds UC84 and UC38 were replaced by an (un) substituted furanyl, thienyl, phenyl, or pyrrole entity have been evaluated for activity against wild-type...

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Dettagli Bibliografici
Pubblicato in:Antimicrob Agents Chemother
Autori principali: Balzarini, J, Brouwer, W G, Dao, D C, Osika, E M, De Clercq, E
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 1996
Soggetti:
Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163349/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8726019/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.40.6.1454
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