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Identification of novel thiocarboxanilide derivatives that suppress a variety of drug-resistant mutant human immunodeficiency virus type 1 strains at a potency similar to that for wild-type virus.

A large variety of carboxanilide and thiocarboxanilide derivatives in which the original oxathiin or aliphatic moieties present in the prototype compounds UC84 and UC38 were replaced by an (un) substituted furanyl, thienyl, phenyl, or pyrrole entity have been evaluated for activity against wild-type...

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Detalles Bibliográficos
Publicado en:Antimicrob Agents Chemother
Principais autores: Balzarini, J, Brouwer, W G, Dao, D C, Osika, E M, De Clercq, E
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 1996
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163349/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8726019/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.40.6.1454
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