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In vivo trypanocidal activities of new S-adenosylmethionine decarboxylase inhibitors.

A series of novel aromatic derivatives based on the structure of methylglyoxal bis(guanylhydrazone) (MGBG) was examined for trypanocidal activities in human and veterinary trypanosomes of African origin. One agent, CGP 40215A, a bicyclic analog of MGBG which also resembles the diamidines diminazene...

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Bibliografske podrobnosti
izdano v:Antimicrob Agents Chemother
Principais autores: Bacchi, C J, Brun, R, Croft, S L, Alicea, K, Bühler, Y
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 1996
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163348/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8726018/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.40.6.1448
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