In vivo trypanocidal activities of new S-adenosylmethionine decarboxylase inhibitors.

A series of novel aromatic derivatives based on the structure of methylglyoxal bis(guanylhydrazone) (MGBG) was examined for trypanocidal activities in human and veterinary trypanosomes of African origin. One agent, CGP 40215A, a bicyclic analog of MGBG which also resembles the diamidines diminazene...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Bacchi, C J, Brun, R, Croft, S L, Alicea, K, Bühler, Y
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1996
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163348/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8726018/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.40.6.1448
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