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Comparative kinetic analyses of interaction of inhibitors with Rauscher murine leukemia virus and human immunodeficiency virus reverse transcriptases.

The inhibitory effects of several nucleoside triphosphate analogs on Rauscher murine leukemia virus (RMuLV) and human immunodeficiency virus (HIV) type 1 reverse transcriptases (RTs) were studied. With RNA as the template, the apparent K(m) and apparent K(i) values of HIV RT toward its substrates an...

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Udgivet i:Antimicrob Agents Chemother
Principais autores: Cherrington, J M, Fuller, M D, Mulato, A S, Allen, S J, Kunder, S C, Ussery, M A, Lesnikowski, Z, Schinazi, R F, Sommadossi, J P, Chen, M S
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1996
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163306/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8723481/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.40.5.1270
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