Selection and characterization of a mutant of feline immunodeficiency virus resistant to 2',3'-dideoxycytidine.

We have selected and plaque purified a mutant of feline immunodeficiency virus (FIV) that is resistant to 2',3'-dideoxycytidine (ddC). This mutant was selected in cultured cells in the continuous presence of 25 microM ddC. The mutant, designated DCR-5c, was fourfold resistant to ddC, threefold resis...

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Publicado en:	Antimicrob Agents Chemother
Autores principales:	Medlin, H K, Zhu, Y Q, Remington, K M, Phillips, T R, North, T W
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Microbiology (ASM) 1996
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163237/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8849258/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.40.4.953
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