Selection and characterization of a mutant of feline immunodeficiency virus resistant to 2',3'-dideoxycytidine.

We have selected and plaque purified a mutant of feline immunodeficiency virus (FIV) that is resistant to 2',3'-dideoxycytidine (ddC). This mutant was selected in cultured cells in the continuous presence of 25 microM ddC. The mutant, designated DCR-5c, was fourfold resistant to ddC, three...

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Bibliographic Details
Main Authors: Medlin, H K, Zhu, Y Q, Remington, K M, Phillips, T R, North, T W
Format: Artigo
Language:Inglês
Published: 1996
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC163237/
https://ncbi.nlm.nih.gov/pubmed/8849258
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