Influence of experimental rat model of multiple organ dysfunction on cefepime and amikacin pharmacokinetics.

We adapted an experimental model of multiple organ dysfunction to study the alterations it induces in the pharmacology of cefepime and amikacin. The half-lives of both antibiotics were significantly prolonged because of nonsignificant enhancement of the volume of distribution and reduced renal elimi...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Mimoz, O, Jacolot, A, Padoin, C, Quillard, J, Tod, M, Louchahi, K, Samii, K, Petitjean, O
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1996
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC163210/
https://ncbi.nlm.nih.gov/pubmed/8851623
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi