Antiviral efficacy in vivo of the anti-human immunodeficiency virus bicyclam SDZ SID 791 (JM 3100), an inhibitor of infectious cell entry.

SID 791, a bicyclam inhibiting human immunodeficiency virus (HIV) replication in vitro by blocking virus entry into cells, is an effective inhibitor of virus production and of depletion of human CD4+ T cells in HIV type 1-infected SCID-hu Thy/Liv mice. Steady levels of 100 ng of SID 791 or higher pe...

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Bibliografiske detaljer

Udgivet i:	Antimicrob Agents Chemother
Principais autores:	Datema, R, Rabin, L, Hincenbergs, M, Moreno, M B, Warren, S, Linquist, V, Rosenwirth, B, Seifert, J, McCune, J M
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 1996
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163192/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8851605/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.40.3.750
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