Antiviral efficacy in vivo of the anti-human immunodeficiency virus bicyclam SDZ SID 791 (JM 3100), an inhibitor of infectious cell entry.

SID 791, a bicyclam inhibiting human immunodeficiency virus (HIV) replication in vitro by blocking virus entry into cells, is an effective inhibitor of virus production and of depletion of human CD4+ T cells in HIV type 1-infected SCID-hu Thy/Liv mice. Steady levels of 100 ng of SID 791 or higher pe...

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Detalhes bibliográficos
Main Authors: Datema, R, Rabin, L, Hincenbergs, M, Moreno, M B, Warren, S, Linquist, V, Rosenwirth, B, Seifert, J, McCune, J M
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC163192/
https://ncbi.nlm.nih.gov/pubmed/8851605
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