In vivo selection of porin-deficient mutants of Klebsiella pneumoniae with increased resistance to cefoxitin and expanded-spectrum-cephalosporins.

Four Klebsiella pneumoniae isolates (LB1, LB2, LB3, and LB4) with increased antimicrobial resistance were obtained from the same patient. The four isolates were indistinguishable in biotype, plasmid content, lipopolysaccharide, and DNA analysis by pulse-field gel electrophoresis. Isolate LB1 made TE...

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Veröffentlicht in:	Antimicrob Agents Chemother
Hauptverfasser:	Martínez-Martínez, L, Hernández-Allés, S, Albertí, S, Tomás, J M, Benedi, V J, Jacoby, G A
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1996
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163113/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8834877/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.40.2.342
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