In vivo selection of porin-deficient mutants of Klebsiella pneumoniae with increased resistance to cefoxitin and expanded-spectrum-cephalosporins.

Four Klebsiella pneumoniae isolates (LB1, LB2, LB3, and LB4) with increased antimicrobial resistance were obtained from the same patient. The four isolates were indistinguishable in biotype, plasmid content, lipopolysaccharide, and DNA analysis by pulse-field gel electrophoresis. Isolate LB1 made TE...

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Bibliographic Details

Published in:	Antimicrob Agents Chemother
Main Authors:	Martínez-Martínez, L, Hernández-Allés, S, Albertí, S, Tomás, J M, Benedi, V J, Jacoby, G A
Format:	Artigo
Language:	Inglês
Published:	American Society for Microbiology (ASM) 1996
Subjects:	Research Article
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163113/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8834877/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.40.2.342
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