In vivo selection of porin-deficient mutants of Klebsiella pneumoniae with increased resistance to cefoxitin and expanded-spectrum-cephalosporins.

Four Klebsiella pneumoniae isolates (LB1, LB2, LB3, and LB4) with increased antimicrobial resistance were obtained from the same patient. The four isolates were indistinguishable in biotype, plasmid content, lipopolysaccharide, and DNA analysis by pulse-field gel electrophoresis. Isolate LB1 made TE...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Martínez-Martínez, L, Hernández-Allés, S, Albertí, S, Tomás, J M, Benedi, V J, Jacoby, G A
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163113/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8834877/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.40.2.342
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