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Effective ribavirin concentration in hamster brains for antiviral chemotherapy for subacute sclerosing panencephalitis.

The ribavirin concentration in hamster brains was measured by a high-performance liquid chromatography (HPLC) system and a bioassay system. When ribavirin was administered intracranially at a dosage of 10 mg/kg of body weight per day for 10 days, a dosage which results in 100% survival of hamsters i...

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Bibliografische gegevens
Hoofdauteurs: Ishii, T, Hosoya, M, Mori, S, Shigeta, S, Suzuki, H
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1996
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC163092/
https://ncbi.nlm.nih.gov/pubmed/8787915
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