Effective ribavirin concentration in hamster brains for antiviral chemotherapy for subacute sclerosing panencephalitis.

The ribavirin concentration in hamster brains was measured by a high-performance liquid chromatography (HPLC) system and a bioassay system. When ribavirin was administered intracranially at a dosage of 10 mg/kg of body weight per day for 10 days, a dosage which results in 100% survival of hamsters i...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Ishii, T, Hosoya, M, Mori, S, Shigeta, S, Suzuki, H
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1996
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163092/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8787915/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.40.1.241
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