Effective ribavirin concentration in hamster brains for antiviral chemotherapy for subacute sclerosing panencephalitis.
The ribavirin concentration in hamster brains was measured by a high-performance liquid chromatography (HPLC) system and a bioassay system. When ribavirin was administered intracranially at a dosage of 10 mg/kg of body weight per day for 10 days, a dosage which results in 100% survival of hamsters i...
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| Publicado no: | Antimicrob Agents Chemother |
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| Principais autores: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
1996
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163092/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8787915/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.40.1.241 |
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