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Selection Acts on DNA Secondary Structures to Decrease Transcriptional Mutagenesis
Single-stranded DNA is more subject to mutation than double stranded. During transcription, DNA is transiently single stranded and therefore subject to higher mutagenesis. However, if local intra-strand secondary structures are formed, some bases will be paired and therefore less sensitive to mutati...
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| Hlavní autoři: | , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Public Library of Science
2006
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1630709/ https://ncbi.nlm.nih.gov/pubmed/17083275 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.0020176 |
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