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K(+) Conduction in the Selectivity Filter of Potassium Channels Is Monitored by the Charge Distribution along Their Sequence

Potassium channels display a high conservation of sequence of the selectivity filter (SF), yet nature has designed a variety of channels that present a wide range of absolute rates of K(+) permeation. In KcsA, the structural archetype for K channels, under physiological concentrations, two K(+) ions...

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Detalhes bibliográficos
Main Authors: Treptow, Werner, Tarek, Mounir
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1630468/
https://ncbi.nlm.nih.gov/pubmed/16980355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.095992
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