MS-8209, a new amphotericin B derivative, provides enhanced efficacy in delaying hamster scrapie.

To test the efficacy of a new amphotericin B derivative, MS-8209, in delaying scrapie, hamsters were infected intracerebrally with the 263K scrapie agent and treated with MS-8209 either early in the course of the disease or continuously. The results show that (i) all treatments lengthened the incuba...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Adjou, K T, Demaimay, R, Lasmezas, C, Deslys, J P, Seman, M, Dormont, D
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1995
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163037/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8593027/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.39.12.2810
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