MS-8209, a new amphotericin B derivative, provides enhanced efficacy in delaying hamster scrapie.

To test the efficacy of a new amphotericin B derivative, MS-8209, in delaying scrapie, hamsters were infected intracerebrally with the 263K scrapie agent and treated with MS-8209 either early in the course of the disease or continuously. The results show that (i) all treatments lengthened the incuba...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Adjou, K T, Demaimay, R, Lasmezas, C, Deslys, J P, Seman, M, Dormont, D
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1995
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC163037/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8593027/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.39.12.2810
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