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MS-8209, a new amphotericin B derivative, provides enhanced efficacy in delaying hamster scrapie.

To test the efficacy of a new amphotericin B derivative, MS-8209, in delaying scrapie, hamsters were infected intracerebrally with the 263K scrapie agent and treated with MS-8209 either early in the course of the disease or continuously. The results show that (i) all treatments lengthened the incuba...

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Détails bibliographiques
Auteurs principaux: Adjou, K T, Demaimay, R, Lasmezas, C, Deslys, J P, Seman, M, Dormont, D
Format: Artigo
Langue:Inglês
Publié: 1995
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC163037/
https://ncbi.nlm.nih.gov/pubmed/8593027
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