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The Immunosuppressant Rapamycin Represses Human Immunodeficiency Virus Type 1 Replication
The immunosuppressive macrolide rapamycin is used in humans to prevent graft rejection. This drug acts by selectively repressing the translation of proteins that are encoded by an mRNA bearing a 5′-polypyrimidine tract (e.g., ribosomal proteins, elongation factors). The human immunodeficiency virus...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC128699/ https://ncbi.nlm.nih.gov/pubmed/12384349 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.11.3447-3455.2002 |
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