The Immunosuppressant Rapamycin Represses Human Immunodeficiency Virus Type 1 Replication

The immunosuppressive macrolide rapamycin is used in humans to prevent graft rejection. This drug acts by selectively repressing the translation of proteins that are encoded by an mRNA bearing a 5′-polypyrimidine tract (e.g., ribosomal proteins, elongation factors). The human immunodeficiency virus...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Roy, Jocelyn, Paquette, Jean-Sébastien, Fortin, Jean-François, Tremblay, Michel J.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2002
Soggetti:	Antiviral Agents
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC128699/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12384349/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.11.3447-3455.2002
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