The Immunosuppressant Rapamycin Represses Human Immunodeficiency Virus Type 1 Replication

The immunosuppressive macrolide rapamycin is used in humans to prevent graft rejection. This drug acts by selectively repressing the translation of proteins that are encoded by an mRNA bearing a 5′-polypyrimidine tract (e.g., ribosomal proteins, elongation factors). The human immunodeficiency virus...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Roy, Jocelyn, Paquette, Jean-Sébastien, Fortin, Jean-François, Tremblay, Michel J.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2002
Assuntos:	Antiviral Agents
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC128699/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12384349/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.46.11.3447-3455.2002
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