Effective High-Capacity Gutless Adenoviral Vectors Mediate Transgene Expression in Human Glioma Cells

Glioblastoma multiforme (GBM) is the most common subtype of primary malignant brain tumor. Although serotype 5 adenoviral vectors (Ads) have been used successfully in clinical trials for GBM, the capacity of Ads to infect human glioma cells and the expression of adenoviral receptors in GBM cells hav...

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Hauptverfasser: Candolfi, Marianela, Curtin, James F., Xiong, Wei-Dong, Kroeger, Kurt M., Liu, Chunyan, Rentsendorj, Altan, Agadjanian, Hasmik, Medina-Kauwe, Lali, Palmer, Donna, Ng, Philip, Lowenstein, Pedro R., Castro, Maria G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2006
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1629029/
https://ncbi.nlm.nih.gov/pubmed/16798098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2006.05.006
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