Effects of Asp-179 mutations in TEMpUC19 beta-lactamase on susceptibility to beta-lactams.
To examine the effect of disruption of the salt bridge (between Arg-164 and Asp-179 [numbering of Ambler et al. (Biochem J. 267:269-272, 1991)]) that anchors the conserved omega-loop in class A beta-lactamases, we obtained mutant enzymes with each of the 19 other amino acid residues replacing Asp-17...
I tiakina i:
| I whakaputaina i: | Antimicrob Agents Chemother |
|---|---|
| Ngā kaituhi matua: | , , , , |
| Hōputu: | Artigo |
| Reo: | Inglês |
| I whakaputaina: |
American Society for Microbiology (ASM)
1995
|
| Ngā marau: | |
| Urunga tuihono: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC162846/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7486939/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.39.8.1878 |
| Ngā Tūtohu: |
Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!
|