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In vivo activity and pharmacodynamics of cefotaxime or ceftriaxone in combination with fosfomycin in fibrin clots infected with highly penicillin-resistant Streptococcus pneumoniae.

Using a clinical pneumococcal strain for which MICs were 2, 0.5, 0.5, and 16 mg/liter for penicillin, cefotaxime, ceftriaxone, and fosfomycin, respectively, we studied the efficacies of these antibiotics alone and in combination in one or two doses or in continuous infusion over 6 h in the treatment...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Chavanet, P, Beloeil, H, Pechinot, A, Duigou, F, Buisson, J C, Duong, M, Neuwirth, C, Kazmierczak, A, Portier, H
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC162818/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7486911/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.39.8.1736
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