In vivo activity and pharmacodynamics of cefotaxime or ceftriaxone in combination with fosfomycin in fibrin clots infected with highly penicillin-resistant Streptococcus pneumoniae.

Using a clinical pneumococcal strain for which MICs were 2, 0.5, 0.5, and 16 mg/liter for penicillin, cefotaxime, ceftriaxone, and fosfomycin, respectively, we studied the efficacies of these antibiotics alone and in combination in one or two doses or in continuous infusion over 6 h in the treatment...

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Detalhes bibliográficos
Main Authors: Chavanet, P, Beloeil, H, Pechinot, A, Duigou, F, Buisson, J C, Duong, M, Neuwirth, C, Kazmierczak, A, Portier, H
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC162818/
https://ncbi.nlm.nih.gov/pubmed/7486911
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