Evaluation of retinal toxicity and efficacy of the anticytomegalovirus compound 2-amino-7-[(1,3-dihydroxy-2-propoxy)methyl]purine.

Compound 2242, also known as 2-amino-7-[(1,3-dihydroxy-2-propoxy)methyl]purine, is the first known antivirally active nucleoside analog with the side chain substituted at the N-7 position of the purine ring system. Our purpose was to evaluate its retinal toxicity and assess the efficacy of its highe...

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Détails bibliographiques

Publié dans:	Antimicrob Agents Chemother
Auteurs principaux:	Besen, G, Chavez-de la Paz, E, Tatebayashi, M, Flores-Aguilar, M, Gangan, P A, Munguia, D, Wiley, C A, Jähne, G, Winkler, I, Helsberg, M
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 1995
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC162767/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7492090/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.39.7.1485
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