Evaluation of retinal toxicity and efficacy of the anticytomegalovirus compound 2-amino-7-[(1,3-dihydroxy-2-propoxy)methyl]purine.

Compound 2242, also known as 2-amino-7-[(1,3-dihydroxy-2-propoxy)methyl]purine, is the first known antivirally active nucleoside analog with the side chain substituted at the N-7 position of the purine ring system. Our purpose was to evaluate its retinal toxicity and assess the efficacy of its highe...

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Библиографические подробности
Главные авторы: Besen, G, Chavez-de la Paz, E, Tatebayashi, M, Flores-Aguilar, M, Gangan, P A, Munguia, D, Wiley, C A, Jähne, G, Winkler, I, Helsberg, M
Формат: Artigo
Язык:Inglês
Опубликовано: 1995
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC162767/
https://ncbi.nlm.nih.gov/pubmed/7492090
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